Silent myocardial ischemia and related risk factors in patients with type 2 diabetes mellitus Mehmet Zorlu 1, Ayşen Helvacı 1, Muharrem Kıskaç 1, Servet Yolbaş 1, Cüneyt Ardıç 2, Mustafa Oran 3, Mine Adaş 1 1 - Okmeydanı Eğitim Araştırma Hastanesi, İç Hastalıkları, İstanbul 2 - Haseki Eğitim Araştırma Hastanesi, Aile Hekimliği, İstanbul 3 - Cerrahpaşa Tıp Fakültesi, İç Hastalıkları ABD, İstanbul
Dicle Med J 2010; 37(2):140-144 ICID: 911566
Article type: Original article
IC™ Value: 6.54
Abstract provided by Publisher
Objectives: The aim of this study was to investigate the frequency of silent myocardial ischemia (SMI) in patients with type 2 diabetes mellitus (DM) who do not have ischemic cardiac disease. Materials and Methods: To examine the relationship between ischemic cardiac disease and related factors such as blood pressure, lipid profile, smoking, gender, family history, body mass index (BMI), microalbuminuria, hsCRP, 150 diabetic patients who have never had any known coroner artery disease, exertional or rest dyspnea and labored breathing, aged between 35 and 70 years were included. Effort testing (treadmill) were performed to examine the existence of SMI. Results: Effort testing gave positive result for SMI in 20 patients and negative in 130 patients. Coronary angiography was performed in 20 patients with positive effort testing results. The frequency of SMI was found as %13.3 by effort testing. The frequency of SMI (including non-critical patients) was %10.6 (16 patients) by using coronary angiography, which 13(8.6%) had critical and 3(2%) had non-critical coronary stenosis. No significant differences were found in age, gender, diabetic duration, trigliserid, HDL- cholesterol, blood pressure, BMI and hsCRP levels between positive and negative SMI patients with Type 2 DM. Conclusion: We determined that high LDL-Cholesterol and HbA1c and existence of microalbuminuria indicated significant SMI risk for patients with Type 2 DM.