Splenectomy in patients with idiopathic thrombocytopenic purpura: Analysis of 109 cases Akın Önder 1, Murat Kapan 1, Mesut Gül 1, İbrahim Aliosmanoğlu 1, Zülfü Arıkanoğlu 1, Fatih Taşkesen 1, İlhan Taş 1, Enver Ay 1, Sadullah Girgin 1 1 - Dicle Üniversitesi Tıp Fakültesi Genel Cerrahi Anabilim Dalı, Diyarbakır, Türkiye
Dicle Med J 2012; 39(1):49-53 ICID: 986926
Article type: Original article
IC™ Value: 3.00
Abstract provided by Publisher
Objectives: Splenectomy is performed in order to provide
the treatment in the patients with severe idiopathic thrombocytopenic
purpura, refractory to medical treatment. In this
study, we aimed to investigate the postoperatif and longterm
outcomes in the patients who underwent splenectomy
with the diagnosis of idiopathic thrombocytopenic purpura.
Materials and Methods: Between 2001-2010 at Dicle University
Medical Faculty, General Surgery Department, a retrospective
review of the 109 patients who had undergone
splenectomy for ITP was reviewed. Age, gender, presence
of accessory spleens and location, duration of the operation,
number of preoperative platelet tranfusion, number of
preoperative and postoperative blood transfusion, length of
hospital stay, long-term outcomes, morbidity and mortality
Results: The mean age was 37.10 ± 16.62 (16-72), and
there were 88 (80.7%) female and 21 (19.3%) male patients.
The mean operation time was 44.87 ± 10:32 (30-120)
minutes. The average postoperative blood and preoperative
platelet transfusion were 1.63 ± 0.85 (0-3) and 2.01 ±
0.71 (1-3) units, respectively. The accessory spleens were
encountered in 20 (18.3%) patients at the ultrasonographic
examination. And also the accessory spleens were encountered
in 23 (21.1%) patients during operation and confirmed
with histopathologic examination. The most common
localization of accessory spleens were splenic hilus. The
postoperative complications were occurred in 16 patients
(14.7%) and the most complication was atelectasia. The
mean length of hospital stay was 4:56 ± 2:45 (2-12) days.
Patients were followed for an average of 28 (9-48) months.
At the follow-up period, 1 (0.9 %) patient had died.
Conclusion: Splenectomy can be performed safely in the
treatment of the patients with idiopathic thrombocytopenic
purpura unresponsive to medical treatment. Long-term
good results can be obtained with splenectomy in these patients.
The accessory spleens should not be overlooked to